Most Democratic-led states say they will continue to universally recommend and administer the hepatitis B vaccine at birth, despite new guidance against it issued last week by a federal vaccine advisory panel handpicked by Health and Human Services secretary Robert F. Kennedy Jr.

The Northeast Public Health Collaborative and the West Coast Health Alliance, which formed earlier this year in response to Kennedy’s concerning overhaul of vaccine policy, along with a other blue states, plan to to defy the latest recommendations made by the Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices, or ACIP.

Hepatitis B is a serious, incurable infection that can lead to liver damage and liver cancer. It can be passed from mother to child during delivery, and without vaccination, about 90 percent of infants infected at birth develop chronic hepatitis B infection. Among those with chronic infection, 25 percent will die prematurely from the disease.

Since 1991, ACIP and the American Academy of Pediatrics have recommended a universal dose of the hepatitis B vaccine within 24 hours after birth. The sooner a newborn gets the vaccine, the higher the chance of preventing chronic infection. The birth dose is credited with dramatically lowering infection rates in children. Yet last week, Kennedy’s newly formed ACIP, which includes several vaccine skeptics, overturned that 30-year precedent. In June, Kennedy announced a “clean sweep” of ACIP, removing all of its previous 17 experts and replacing them with new members of his choosing.

During a chaotic two-day meeting th...